Breed Health

Border Terrier at vet

2024 Annual Breed Health Report

BREED HEALTH 2024

There have been no new conditions on the radar this year , those of most concern continuing to be : Spongioform Leucoencephalomyelopathy (SLEM) ,Canine Epileptoid Cramping Syndrome (CECS) ,Gallbladder Mucocoele (GBM) ,Cushing’s Syndrome and late onset Hereditary Cataract.   

The two issues of most interest this year have been the funding crisis experienced by the Canine Genetics Research Centre and the proposed introduction by the Kennel Club of a Health Standard uniquely tailored for every breed.

CANINE GENETICS RESEARCH CENTRE

In January the canine community were shocked by the Kennel Club’s decision to withdraw it’s long-term sponsorship of what was then known as the Kennel Club Canine Genetics Centre based at the University of Cambridge and to enter into an alternative agreement which would see their genetic testing carried out by a commercial firm.

For many years the Kennel Club and the Kennel Club Charitable Trust had been the principal sponsors and their withdrawal of financial support meant that there was a funding deficit of approximately £345,000 for the running of the Genetics Centre for the year 2024.This threatened the future of the organisation and unless alternative funding could be found it was likely that the group would cease to exist.

Dr. Cathryn Mellersh and her team at the Genetics Centre have many years of experience researching inherited canine diseases and have developed a number of DNA tests for some which have enabled breeders to make informed decisions on matings thus saving many dogs from having been born to suffer painful, restricted lives.They are a group well respected within the scientific community and have an excellent international reputation.

As a breed we have directly benefitted from their mapping of the complete canine genome and also from the one carried out specifically for the Border Terrier, a project to which all of our Clubs contributed. They were also involved with the University of Missouri in the development of the DNA test for SLEM and there is a high likelihood that any future research programmes into inherited diseases within our breed would come under their auspices. The Genetics Centre also stores a large number of DNA samples from many  breeds including ours which are available for use by interested researchers.

Dr.Mellersh  reached out toall breeds for help towards this funding crisis and I am pleased to report that most responded positively and pledged financial support. The response from the Border Terrier community was excellent with £3,500 being donated from the Breed Health Fund and generous donations also coming from Border Terrier Welfare and Border Terrier Lifeline. If we can help to keep them afloat it allows more time for them to try and secure a major commercial sponsor or sponsors and also for the wider canine community to come up with ways in which we could provide some long-term financial support. 

The future of the Group is now more secure but they are still in need of further help for long term funding .One of their initiatives has been to introduce a Friends of the CGC scheme whereby any interested individual may set up a direct debit for £5 or more monthly and become a Friend of the CGC. I would encourage as many of our community as possible to become involved as the more who make a small regular contribution the greater the guaranteed regular income . I am sure that everyone would agree that their work has been and continues to be of great importance to the entire canine world , not just those who choose to breed and we must play our part in supporting it. Details of how to join may be accessed via their website on www.canine-genetics.org.uk.

INTRODUCTION OF HEALTH STANDARD

This year the Kennel Club have launched a new initiative, the Health Standard, formulated to help guide breeders as to which health tests should be undertaken prior to breeding from their dogs. Previously the Border Terrier had DNA testing for SLEM as a Recommendation. Under the new proposals there are two categories of test : Good Practice being those tests deemed to be most critical and Best Practice which sees breeders perform those tests advised as Good Practice plus all other recommended tests.

For Border Terriers we have Hip scoring and SLEM testing , both listed in the Best Practice category.

The new scheme is based on worldwide scientific data and and tests are recommended based on the estimated prevalence of a condition within a breed population. In the UK very few Border Terriers are screened for hip dysplasia but data from the USA puts the incidence in tested dogs as being 4 percent, most being moderate or mild. Data from Agria Insurance based on European dogs suggests that Border Terriers have a lower than all breed average for the condition. We do get odd cases reported via the health survey. There is ongoing correspondence between myself and the Health Department of the Kennel Club over this as the Breed Health Group, although agreeing that all health testing is worthwhile are not convinced that hip dysplasia is a significant problem in our breed in the UK. 

SLEM testing will not be upgraded until a peer evaluated review on the research has been published. Dr .Dan Johnston from the University of Missouri who was involved in the development of the DNA test sadly died before a paper was published. A research student is currently re-evaluating the data under the guidance of Dr. Cathryn Mellersh with the aim of producing such a paper. The Kennel Club have promised to review their recommendations on SLEM testing when this is published and have assured breed communities that their Health Standard is a fluid document which can be reviewed as new evidence emerges.

I will keep you updated of any further developments on this front but the Breed Health Group continue to advise SLEM testing as essential due to the large number of carriers present in the population. We would also recommend eye testing  as being worthwhile.

Also of interest to breeders will be the Kennel Club’s Population Analysis Study results which will be made available this coming year.

HEALTH SURVEY

Our ongoing health survey helps us to monitor health conditions within the breed and hopefully pick up on any new conditions which may be emerging. The more questionnaires completed the truer the picture and forms submitted for completely healthy dogs are equally valuable as they help to validate general health status.

This year we had 82 responses to our health surveys including 6 from overseas. These were received from: USA (3) , Germany (1) , Sweden  (1) and New Zealand (1).

7 of the 82 dogs reported on had no known health conditions and overall the owners of 69 of the dogs regarded them as being basically healthy , only 13 being described by their owners as not healthy. A wide range of medical conditions were recorded with a small number of dogs being unfortunate enough to suffer from multiple issues.

I would like to extend my sincere thanks to everyone who has taken the time to complete a questionnaire and would encourage as many owners as possible to follow their lead. Questionnaires can be found on our Breed Health Group site: www.borderterrierhealth.org.uk and either completed online or downloaded and a paper copy sent directly to myself. Confidentiality will be respected if you so wish.

The conditions reported this year (2024) were:

ENDOCRINE (13): Hypothyroidism (2), Diabetes (1), Cushing’s Syndrome (10).

DIGESTIVE (28): Pancreatitis (1), Hepatitis (1),  Liver shunt (1), Inflammatory bowel disease (7), Exocrine Pancreatic Insufficiency (1) ,Gallbladder (17) - Gallbladder mucocoele (14), Sludge (2), Thickening (1).

NEUROLOGICAL (22):  Deafness (2), Spinal injury (1),  Brain tumour (4), Canine Epileptoid Cramping Syndrome (13), Fits other (1) ,Ataxia of unknown origin (1)

NEOPLASIA (9): Mammary tumour (1), Brain tumour (4),  Epuli, (1), Testicular tumour (1), Prostatic tumour (2).

ORTHOPAEDIC (18) : Osteo-arthritis including spinal (10), Limb fractures (1),  Rupture of the anterior cruciate ligament (4) - 2 bilateral and 2 unilateral , Patellar luxation (2) , Unspecified stifle lameness (1).

REPRODUCTIVE (7): Pyometra (1), Caesarean section (1),  Mammary tumours (1), Cryptorchidism (1) - bilateral, Prostatic tumour (2) , Testicular tumour (1) -both testes affected.

BEHAVIOURAL (16): Anxiety (2),  Timidity (1), Destructive behaviour (2), Noise phobic (1), Aggression/reactivity (10)

URINARY (3):  Chronic kidney disease (3), one diagnosed as Glomerulonephritis and a second occurring after Idiopathic Renal Haemorrhage.

CONFORMATIONAL DEFECTS (1): Kinked tail (1)

DENTAL/ORAL (11): Dental with extractions (9),  Gingival hyperplasia (1),  Oral tumours (1) – Epuli (1).

OCULAR (11): Cataracts (5) -1 juvenile, Detached retina (1), Glaucoma (1), Unspecified blindness (2),  Distichiasis (1),  Enucleation (1), 

DERMATOLOGICAL (2):  Allergic dermatitis with otitis (2) .

CARDIOVASCULAR (6): Congestive heart failure (1), Congenital defects (3) - mitral valve dysplasia (1), pulmonic stenosis (1) , aortic stenosis (1), unspecified murmur(1), High blood pressure (1).

Overall Border Terriers have an above average health status with the majority living to a good age. However, there is no room for complacency and it is importance that we all are honest and share any medical information relating to dogs we have bred or owned as this is the best way of preserving the health of our breed.

Eddie Houston B.V.M.S, M.R.C.V.S 

Breed Health Co-ordinator

University of Cambridge Border Terrier gall bladder survey

We would be grateful if you could all help to distribute this link throughout the Border Terrier community.

It relates to a project at Cambridge University which is trying to establish if there any dietary factors common to GBM cases. Replies are welcome from ALL owners, not just from those with affected dogs. If any of them would also care to fill in one of our health questionnaires that would also be most welcome.

Click image for link

GBM Project

Canine Genetics Centre Logo

Canine Genetics Centre Appeal

Please read the appeal from the Canine Genetics Centre.  In addition, an email is being sent (from today) to all Breed Clubs and Canine Societies/Agricultural Societies/Training Clubs/Gundog Clubs etc.

The Border Terrier Breed Health Group will be pledging a donation of £3,500 to the appeal and it is our understanding that Border Terrier LifeLine will also be pledging £1,500 to the appeal.

There is still a long way to go to save the CGC, but every little helps and if individuals can donate and are UK taxpayers, then Government Gift Aid is added to each amount by simply ticking a box on the donation form.

Canine Genetics Centre logo

 

Hello,

As Head of the Canine Genetics Centre at the University of Cambridge, I am reaching out to breed clubs, societies and other canine groups seeking your help and where relevant, your members. I very much hope you will be able to share this email and related links with your organisation’s committee and membership, and I thank you in advance for your interest.

You may already be aware that the Kennel Club and Kennel Club Charitable Trust have announced that they are no longer able to contribute financially to the Canine Genetics Centre (CGC). They have been long term substantial funders for the Centre, supporting our joint objective to improve the genetic health of our dogs. However, their withdrawal of funding from April 2024 has placed the Centre in a precarious position. We need to secure around £345k over the next few months, either as pledged support or direct donations, to keep the Centre running. My team and I are determined not to let the Centre close down – and we are appealing to the grass roots for support.

This is why I hope you will be able to help spread this message and engage your “membership” through whatever means possible.

 

For readers who may be unaware of what we do, here is some context to the appeal:

Sadly, dogs have the highest known occurrence of inherited genetic diseases after humans. At CGC we undertake the genetic research necessary to identify the precise mutations that cause inherited canine disease. Commercial DNA testing laboratories cannot offer tests for specific mutations until the research phase is complete and details of each mutation have been published. Many of you will have had your own dogs DNA tested, but you may not be aware that the tests rely on the research that we, and other research groups around the world, undertake.

Since its inception, the CGC has been at the forefront of canine genetic research, identifying 32 mutations, most of which form the basis of commercially available DNA tests. This output places CGC on par with, or even surpassing, others in the same field – a testament to its dedication to canine health and efficient operation.

Some of the inherited disease mutations identified by CGC include:

  • Primary lens luxation in around 20 different breeds of dogs
  • Progressive retinal atrophy - 7 different mutations in 8 different breeds of dogs
  • Primary open angle glaucoma - 4 different mutations in 4 different breeds of dog
  • Inherited forms of ataxia - four different mutations in 5 different breeds of dog

Appeal

Given our situation, the CGC has launched an appeal with a target to raise £345k to secure the Centre over the next twelve months. These funds are to fill the immediate funding gap and an advisory group, comprised of unpaid volunteers, has been formed to develop a longer-term funding strategy. So, while we encourage Breed Clubs, individual members, breeders and dog owners to engage with the work of the Canine Genetics Centre and fundraise to help support our research in the future, we do not intend to make an appeal on this scale again.

Our Dogs newspaper has dedicated space this week to our appeal launch, aiming to engage enthusiasts across the pedigree dog world. We hope to amplify this through social media and various other support activities, with my team and I making an appearance at Crufts in the next few weeks too. Stay tuned for updates!

How can you contribute?

Breed Clubs and Societies

Please pledge now

We encourage breed clubs, societies and other groups to support us in any way they can. Recognising that some clubs with smaller numbers may face constraints, we've set up an option to pledge on our website. Clubs can also donate in increments, providing flexibility. Complete our Pledge Form here.

Breeders, Owners & Enthusiasts 

Please donate today

Help us broaden our reach by spreading our APPEAL to a wider audience. While Clubs may face constraints, individuals may wish to contribute directly, benefiting from Gift Aid – turning every £1 donated into £1.25. Please encourage direct donations. Individuals can also pledge directly through our Pledge Form.

Illustrative Example

If 50 breeds could find 40 people willing and able to donate £100 each, we would be able to establish a solid foundation, affording us time to implement sustainable and longer-term funding approaches. We understand that £100 might be out of the reach of many, but this is for illustrative purposes and aims to demonstrate that this challenge is more manageable than it appears. We appreciate any donation, regardless of amount as every contribution will have a meaningful impact.

Donate now

International APPEAL:

Genetic mutations transcend borders, impacting breeds globally, not just within the UK. We urge you to spread this APPEAL far and wide, reaching out to overseas Breed Clubs and enthusiasts. Your help in reaching a broader audience will make a significant difference in our collective efforts to resolve our short-term funding issue.

Sharing is caring - please share the APPEAL within your networks.

Finally, we would like to express our sincere thanks for your consideration and support. We apologise if this email reaches more than one member of your committee, or if you are already familiar with our appeal - we are trying to extend our reach as widely as possible.

 

With our warmest wishes,

Cathryn, her team and advisory group

Breed Health Report 2023

BREED HEALTH 2023

There haven’t been any major changes on the health front this year and the conditions regarded as significant continue to be: Spongiform- Leuco-Encephalo-Myelopathy (SLEM), Gallbladder Mucocoele (GBM), Canine Epileptoid Cramping Syndrome (CECS) aka Paroxysmal Gluten Sensitive Dyskinesia (PGSD), Cushing’s Syndrome and late onset Hereditary Cataract.